Introduction. Acne scarring affects thirty percent of world population. Ninety five percent develop acne scarring, which has a profound psychological impact, especially in younger adults. (1-4) Acne scarring occurs due to inflammatory destruction of collagen in the affected areas. P. acnes factors and peptidoglycan dose‑dependently augmented production of proMMP‑2 in sebocytes and dermal fibroblasts, indicating bacterial‑driven induction of MMPs that can degrade ECM and p